Molecular Mechanism of Black Tea (Camellia sinensis) as SARS-CoV-2 Spike Glycoprotein Inhibitor through Computational Approach

Md. Emdad, Ullah and Sin War, Naw and Ahmad Affan, Ali Murtadlo and Muhammad Badrut, Tamam and Rasyadan Taufiq, Probojati (2022) Molecular Mechanism of Black Tea (Camellia sinensis) as SARS-CoV-2 Spike Glycoprotein Inhibitor through Computational Approach. SAIN & TEK, 1 (1). pp. 1-6. ISSN 2690-103X (online)

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Abstraksi

ABSTRACT SARS-CoV-2 infection in humans also causes cytokine storm and can lead to patient death, this condition occurs due to the excessive release of pro-inflammatory cytokines by immune cells. SARS-CoV-2 infects cells in the human respiratory tract. Spike glycoprotein aims to bind to ACE2 in the viral entry process. Several studies have suggested that the SARS-CoV-2 spike is an ideal target for drug design. Camellia sinensis or black tea is a member of the Theaceae family and the genus Camellia. Camellia is a vast genus to East India, the Malay Peninsula, and Southeast Asia, together with Indonesia. In truth, Camellia sinensis is a tropical fruit that has been used as a traditional medicine for hundreds of years globally. This study is to identify the bioactive compounds from Camellia sinensis as an antiviral agent via spike glycoprotein inhibitor mechanisms against the SARS-CoV-2 infection through the in silico approach. Keywords: Antiviral, Bioinformatics, Camellia sinensis, SARS-CoV-2

Item Type:	Article
Uncontrolled Keywords:	Antiviral, Bioinformatics, Camellia sinensis, SARS-CoV-2
Subjects:	Fakultas Sains, Teknologi dan Pendidikan > S1 Biologi
Divisions:	Fakultas Sains, Teknologi dan Pendidikan
Depositing User:	Admin
Date Deposited:	27 Jun 2022 04:42
Last Modified:	27 Jun 2022 04:42
URI:	http://repository.umla.ac.id/id/eprint/1982

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